Biomedical Microdevices
Principles of sensors, actuators, microfluidics, biotechnology and nanotechnology, with applications in probing, detection, assaying, and drug delivery.
3 credits
Course Outline
The course will cover basic principles of sensors, actuators, microfluidics, bio-nanotechnology, with applications in probing, detection, assaying and drug delivery. This course will accommodate students from various backgrounds, providing a short introduction to topics including biology, biochemistry, and neuroscience.
Course Objectives
By the end of the term, students should be able to:
- Compare biomedical microdevices with current macroscale devices.
- Discuss reasons for miniaturization.
- Explain commonly used biosensing principles and describe how they are used in example devices.
- Evaluate current literature: read scientific journal papers, and understand the goals and conclusions.
Course Topics
- Microfabrication basics, rapid prototyping for microfluidic devices
- DNA chips: DNA basics, DNA arrays, on-chip electrophoresis, on-chip PCR
- Protein chips: protein basics, immunosensors, separations
- Neural applications: biophysics basics, on-chip electrophysiology, neuron patterning, microelectrode arrays, microneedles
- Flow cytometry and cell separation
- Mechanical biosensors
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